Organic metal halides
Medchemexpress LLC COB-187 | 1862177-86-3 | 95.0% | 302.41 | 50 MG
COB-187 is a potent, ATP-competitive, and selective inhibitor of GSK-3β. It inhibits GSK-3 through a reversible and Cysteine (Cys)-199-dependent mechanism. COB-187 inhibits LPS-induced cytokine production and SARS-CoV-2 spike protein-induced CXCL10 production.
- Potent, ATP-competitive, and selective inhibitor of GSK-3β.
- Inhibits GSK-3 through a reversible and Cysteine (Cys)-199-dependent mechanism.
- Inhibits LPS-induced cytokine production.
- Inhibits SARS-CoV-2 spike protein-induced CXCL10 production.
Strem, An Ascensus Company CAS# 12012-95-2. 10g. Allylpalladium chloride dimer, min. 98%. MFCD00044874
CAS# 12012-95-2. 10g. Allylpalladium chloride dimer, min. 98%. MFCD00044874. Molecular Weight: 365.86. Molecular Formula: [C3H5PdCl]2. Color/form: yellow xtl. Strem# 46-0100. http://www.strem.com/catalog/v/46-0100/
Medchemexpress LLC Saroglitazar magnesium | 1639792-20-3 | MFCD29075338 | 98.0% | 901.42 | C50H56MgN2O8S2 | 10 MG
Saroglitazar magnesium is the magnesium salt of saroglitazar, a small-molecule peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα activity and moderate PPARγ activity. Supplied as a light-yellow solid for research use, it is used in in vitro and preclinical studies of lipid and glucose metabolism.
- Magnesium salt form of a dual PPARα/PPARγ agonist.
- Useful for pharmacology and mechanistic studies of metabolic pathways.
- Reported molecular weight 901.42 and formula C50H56MgN2O8S2.
- Supplied as a light-yellow solid suitable for laboratory handling.
- Available in small sample sizes for research use.
Medchemexpress LLC Saroglitazar magnesium | 1639792-20-3 | 98.85% | 901.42 | 25 MG
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist that exhibits predominant PPARα activity and moderate PPARγ activity, with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
- Novel peroxisome proliferator-activated receptor (PPAR) agonist
- Predominant PPARα activity (EC50 of 0.65 pM in HepG2 cells)
- Moderate PPARγ activity (EC50 of 3 nM in HepG2 cells)
- Causes dose-dependent reductions in serum triglycerides (TG), free fatty acids (FFA), and glucose in db/db mice
- Shows lipid-lowering effects in preclinical models
- Indicated low risk of PPAR-associated side effects in humans
- Appears to have good potential as a novel therapeutic agent for the treatment of dyslipidemia and diabetes
Medchemexpress LLC BAY-677 | 2117404-84-7 | 98.0% | 400.35 | 10 MG
BAY-677 serves as an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), demonstrating an IC50 of 20 nM. This compound has also been nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
- Inactive control for BAY-678.
- BAY-678 is an orally bioavailable inhibitor.
- Highly potent and selective inhibitor of human neutrophil elastase.
- Cell-permeable.
- IC50 of 20 nM against HNE.
- Nominated as a chemical probe by SGC.
Medchemexpress LLC Aminooxy-PEG3-bromide | 1895922-73-2 | C8H18BrNO4 | 25 MG
Aminooxy-PEG3-bromide is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. These compounds exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system to degrade target proteins
Medchemexpress LLC Benzalkonium bromid 100g
N-Benzyl-N N-dimethyldodecan-1-aminium bromide also known as Benzalkonium Chloride (BAC) is a quaternary ammonium compound widely used as an antimicrobial and surfactant in various industries BAC is commonly used as a disinfectant and antiseptic in a variety of products including hand sanitizers disinfectant wipes and eye drops Its ability to kill bacteria viruses and fungi makes it an effective tool in preventing the spread of infection BAC is also used as a preservative and disinfectant in the food industry It is added to food packaging and processing equipment to prevent the growth of microorganisms and increase the shelf life of foods Additionally BACs are found in many household products such as cleaning solutions fabric softeners and personal care products Its surfactant properties allow it to be used to reduce surface tension and increase the effectiveness of cleaning agents Although BAC has many uses ingestion or exposure to high concentrations of BAC c
Medchemexpress LLC CVT-12012 | 1018675-35-8 | 99.58% | 434.41 | 25 MG
CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM for rat microsomal and 6.1 nM for human HEPG2.
- Potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor.
- Demonstrates good oral bioavailability (78%) in a rat PK study.
- Oral absorption is not significantly affected by Pgp efflux.
Sigma Aldrich Fine Chemicals Biosciences Cyclohexylmagnesium chloride solution 1.0 M in 2-methyltetrahydrofuran | 931-51-1 | MFCD00003816 | 800ML
Cyclohexylmagnesium chloride solution 1.0 M in 2-methyltetrahydrofuran | Mol Wt: 142.91 | 931-51-1 | MFCD00003816 | 800ML
Strem, An Ascensus Company CAS# 133395-16-1. 1g. Magnesium bis(trifluoromethylsulfonyl)imide, min. 97%. MFCD14156020
CAS# 133395-16-1. 1g. Magnesium bis(trifluoromethylsulfonyl)imide, min. 97%. MFCD14156020. Molecular Weight: 584.60. Molecular Formula: Mg[(CF3SO2)2N]2. Color/form: white pwdr. Strem# 12-1200. http://www.strem.com/catalog/v/12-1200/
Medchemexpress LLC Anisotropine bromide | 80-50-2 | 98.0% | 5 MG
Anisotropine bromide, also known as Octatropine bromide, is an orally active anticholinergic muscarinic antagonist. It is capable of inhibiting gastric acid secretion and is employed as an adjunct in the treatment of peptic ulcers. This product is strictly for research use only.
- Anticholinergic muscarinic antagonist
- Inhibits gastric acid secretion
- Used as an adjunct to peptic ulcers
- Blocks acetylcholine-induced vocalization, intestinal spasm, and intestinal contractions
Sigma Aldrich Fine Chemicals Biosciences Cyclohexylmagnesium chloride solution 1.0 M in 2-methyltetrahydrofuran | 931-51-1 | MFCD00003816 | 4X25ML
Cyclohexylmagnesium chloride solution 1.0 M in 2-methyltetrahydrofuran | Mol Wt: 142.91 | 931-51-1 | MFCD00003816 | 4X25ML